Alkahest is developing therapies derived from blood and its components with a focus to improve vitality and function into old age. We are working on treatments for diseases of aging, with an emphasis on cognitive dysfunction and dementia, which are key medical challenges of our generation. The company’s pioneering research has demonstrated that factors in young plasma are able to reverse brain deficits in preclinical models relevant to normal aging and Alzheimer’s disease. Conversely, inhibition of factors that are present in old plasma can improve brain functions in preclinical models of age-related cognitive decline. The Company is conducting clinical studies in patients with different types of dementia and other neurodegenerative diseases. Alkahest is a private company based in San Carlos, CA, with investors including Barcelona, Spain-based Grifols, a global healthcare company and leading producer of plasma therapies, also a collaboration and commercialization partner.